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    Aus Wissen wird Gesundheit

  • Link zur Klinik für Hals-, Nasen-,- Ohrenheilkunde

    Hörimplantate: einzigartige Hörsysteme

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  • Link zum Zentrum der Neurologie und Neurochirurgie

    Aktive Neuroprothese: lässt Schlaganfallpatienten wieder richtig gehen

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  • Link zur Pressemitteilung "Patientenblut-Management"

    PBM

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  • Link zur Pressemitteilung "Kleinster Lebensretter der Welt jetzt in Frankfurt"

    Minimalisierte Technik der Herzmedizin: kleinster Implantierbarer Defibrillator der Welt und Mini-Herzmonitor am Uniklinikum im Einsatz

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    Ultraschallbehandlung von Schilddrüsenknoten: erstmals non-invasive Entfernung

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  • Link zur Homepage des Institut für Diagnostische und Interventionelle Radiologie

    Star Ablation: Radiofrequenzstrahlung stabilisiert brüchige Knochen

Programm

March 23, 2010

Transfer from the airport, referent dinner

March 24, 2010

10.00 - 10.15 Welcome
Wolfgang Wick, Karl Plate und Joachim Steinbach
Scientific Organizing Committee
10.15 - 10.30 INTRODUCTION:
Current Issues in Neurooncology
Otmar Wiestler
Chairman and Scientific Director German Cancer Research Center

11.00 – 13.00 Session 1: Individualizing brain tumor therapy
Chairs: W.K. Cavenee/ J. Steinbach
11.00 – 11.30 Profiling malignant Glioma I: The genetic basis of the disease
Webster K .Cavenee
11.30 12.00 Innovative techniques for high-throughput analyses
Peter Lichter
12.00 – 12.30 Profiling malignant Glioma II: Implications for the design of molecular therapies
Tracy Batchelor
12.30 – 13.00 Current clinical trials with molecular therapies
Wolfgang Wick
13.00 – 13.30 Plenary Discussion: Individualizing molecular therapies
13.30 – 14.30 Lunch Break
14.30 – 19.00 Session 2: Molecular & cellular pathology of  gliomas
Chairs: Andreas von Deimling/ Ulrich Bogdahn
14.30 – 15.00 Genetics of glioma progression and the definition of primary and secondary glioblastoma
Hiroko Ohgaki
15.00 – 15.30 IDH1/2 mutations in gliomas
Andreas von Deimling
15.30 – 15.50 Profiling of childhood brain tumors
Stefan Pfister
15.50 – 17.00 Coffee Break and Poster Session
17.00 – 17.30 The role of epigenetic alterations and miRNAs in glioma biology
GuidoReifenberger
17.30 – 18.00 Mechanisms of cell death in gliomas I: Apoptosis
Simone Fulda
18.00 – 18.20 Non-apoptotic functions of cell death-associated factors
Ana Martin-Villalba
18.20 – 18.40 Mechanisms of cell death in gliomas II: Autophagy
Donat Kögel
18.40 – 19.00 Plenary Discussion: Molecular Pathology
19.00 Dinner
20.00 Business Meeting Frankfurt/Heidelberg Brain Tumor Research Consortium

March 25, 2010

8.00 – 10.30 Session 3: Glioma stem cells
Chairs: Roger McLendon/Andreas Trumpp
8.00 – 8.30 Glioblastoma stem cells: an organizational approach
Roger McLendon
8.30 – 9.00 Profiling of glioblastoma stem cell lines
Manfred Westphal
9.00 – 9.30 The concept of stem cell dormancy
Andreas Trumpp
9.30 – 10.00 Mechanisms and relevance of neural lineage differentiation in gliomas
Heidi Philips
10.00 – 10.30 Plenary Discussion: Brain cancer stem cells
10.30 – 11.00 Coffee Break
11.00 – 13.00 Session 4: Angiogenesis and metabolism
Chair: Karl-H. Plate/Wolfgang Wick
11.00 – 11.30 Metabolism as a novel tumor-specific target of therapy
Thomas Seyfried
11.30 – 12.00
Perspectives for the development of anti-angiogenic therapies
Karl Plate
12.00 – 12.30
Hypoxia-induced resistance towards targeted therapies
Joachim Steinbach
12.30 – 13.00 Plenary Discussion: Angiogenesis and metabolism
13.00 – 14.00 Lunch
14.00 – 16.45 Session 5: Virus and immune therapies for malignant  gliomas
Chair: Michael Platten/Dorothee von Laer
14.00 – 14.30 Gene therapy: current concepts and applications for glioma therapy
Christoph von Kalle
14.30 – 15.00 Oncolytic virus therapy of glioblastoma with pseudotyped VSV vectors
Dorothee von Laer
15.00 – 15.30 TGF-beta: an effector of tumor-mediated immune escape
Ulrich Bogdahn
15.30 – 15.50 The role of tryptophan metabolites for glioma immune biology
Michael Platten
15.50 – 16.10 Immunologic approaches towards glioma stem cells
Christel Herold-Mende
16.10 – 16.30
Engineered measles virus as gene therapy for glioma
Guy Ungerechts
16.30 – 16.45 Plenary Discussion: Virus and immune therapies for malignant glioma
16.45 – 17.00 Coffee break
17.00 – 19.00 Session 6: Selected short presentations
Chair: Jörg-Christian Tonn/ Andreas Unterberg
19.30 20:00
Apero
20.00 21.00 Dinner Buffet
21.00 22:00
EVENING LECTURE:
“The history of brain tumor research”

Paul Kleihues
22.00
Social Evening
with the Band Jazzvisite + DJ

March 26, 2010

8.30 – 11.15
Session 7: Brain tumor models
Chairs: Manfred Westphal/Volker Seifert
8.30 – 9.00 Stem-like cells and the perivascular niche
Eric Holland
9.00 – 9.30 Xenografting human gliomas from biopsy material: Current concepts
Rolf Bjerkvig
9.30 - 10.00 Mechanisms and models for anti-Integrin therapy
Jörg-Christian Tonn
10.00 – 10.30 Mechanisms of response and resistance to anti-VEGF therapy
Frank Winkler
10.30 – 11.00 Novel therapeutic strategies for glioma patients after failure of bevacizumab
Lauren Abrey
11.00 – 11.15 Plenary Discussion: Preclinical brain tumor models
11.15 – 11.30 Coffee Break
11.30 – 12.00 Session 8: Poster Prize Award
Chair: Michael Weller
12.00 – 12.30
CLINICAL PRACTICE LECTURE:
Current standards of therapy for malignant gliomas and emerging concepts

Michael Weller
12.30 – 13.00
Plenary Discussion: Current standards of therapy
13.00 – 13.15 Closing remarks and summary
Wolfgang Wick, Karl Plate und Joachim Steinbach
13.15 – 14.00 Lunch buffet & departures
14.00 – 15.30 Steering Committee Frankfurt/Heidelberg Brain Tumor Research Consortium

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