Molecular Gynaecology

Cancer cells originate from a former individual healthy cell. During the process of becoming a neoplastic disease the genetic material has undergone several changes in the form of mutations. These mutations occurring in a highly diverse multi-step process providing new biological capabilities. They include sustained proliferation, unrestricted growth, evasion of apoptosis, enabling replicative immortality, inducing angiogenesis, and activating invasion and metastasis. These capabilities which are termed the "The Hallmarks of Cancer" were recently extended by two additional ones: "reprogramming of energy metabolism and evading immune de