Aktuelle Publikationen

aktuelle Publikationen


RITA Is Expressed in Trophoblastic Cells and Is Involved in Differentiation Processes of the Placenta.

Wildner JM, Friemel A, Jennewein L, Roth S, Ritter A, Schüttler C, Chen Q, Louwen F, Yuan J, Kreis NN.Cells. 2019 Nov 21;8(12). pii: E1484. doi: 10.3390/cells8121484.PMID:31766533


Subcutaneous and Visceral Adipose-Derived Mesenchymal Stem Cells: Commonality and Diversity.

Ritter A, Friemel A, Roth S, Kreis NN, Hoock SC, Safdar BK, Fischer K, Möllmann C, Solbach C, Louwen F, Yuan J.,Cells. 2019 Oct 21;8(10). pii: E1288. doi: 10.3390/cells8101288.PMID:31640218


The Multifaceted p21 (Cip1/Waf1/CDKN1A) in Cell Differentiation, Migration and Cancer Therapy.

Kreis NN, Louwen F, Yuan J.Cancers (Basel). 2019 Aug 21;11(9). pii: E1220. doi: 10.3390/cancers11091220. Review.PMID:31438587


Restoration of primary cilia in obese adipose-derived mesenchymal stem cells by inhibiting Aurora A or extracellular signal-regulated kinase.

Ritter A, Kreis NN, Roth S, Friemel A, Jennewein L, Eichbaum C, Solbach C, Louwen F, Yuan J.Stem Cell Res Ther. 2019 Aug 14;10(1):255. doi: 10.1186/s13287-019-1373-z.PMID:31412932


RITA modulates cell migration and invasion by affecting focal adhesion dynamics.

Hoock SC, Ritter A, Steinhäuser K, Roth S, Behrends C, Oswald F, Solbach C, Louwen F, Kreis NN, Yuan J.Mol Oncol. 2019 Oct;13(10):2121-2141. doi: 10.1002/1878-0261.12551. Epub 2019 Aug 6.PMID:31353815


Function of p21 (Cip1/Waf1/CDKN1A) in Migration and Invasion of Cancer and Trophoblastic Cells.

Kreis NN, Friemel A, Ritter A, Roth S, Rolle U, Louwen F, Yuan J.Cancers (Basel). 2019 Jul 15;11(7). pii: E989. doi: 10.3390/cancers11070989.PMID:31311187


Potential involvement of RITA in the activation of Aurora A at spindle poles during mitosis.

Kreis NN, Steinhäuser K, Ritter A, Klöble P, Hoock SC, Roth S, Louwen F, Oswald F, Yuan J.Oncogene. 2019 May;38(22):4199-4214. doi: 10.1038/s41388-019-0716-7. Epub 2019 Jan 31.PMID:30705408


Deficient primary cilia in obese adipose-derived mesenchymal stem cells: obesity, a secondary ciliopathy?

Ritter A, Louwen F, Yuan J.Obes Rev. 2018 Oct;19(10):1317-1328. doi: 10.1111/obr.12716. Epub 2018 Jul 17. Review.PMID:30015415


Insight into the development of obesity: functional alterations of adipose-derived mesenchymal stem cells.

Louwen F, Ritter A, Kreis NN, Yuan J.Obes Rev. 2018 Jul;19(7):888-904. doi: 10.1111/obr.12679. Epub 2018 Mar 8. Review.PMID:29521029


Primary Cilia Are Dysfunctional in Obese Adipose-Derived Mesenchymal Stem Cells.

Ritter A, Friemel A, Kreis NN, Hoock SC, Roth S, Kielland-Kaisen U, Brüggmann D, Solbach C, Louwen F, Yuan J.Stem Cell Reports. 2018 Feb 13;10(2):583-599. doi: 10.1016/j.stemcr.2017.12.022. Epub 2018 Jan 27.PMID:29396182

11.Rödel F, Steinhäuser K, Kreis NN, Friemel A, Martin D, Wieland U, Rave-Fränk M, Balermpas P, Fokas E, Louwen F, Rödel C, Yuan J. Prognostic impact of RITA expression in patients with analsqamous cell carcinoma treated with chemoradiotherapy. Radiother Oncol. 2018 Feb;126(2):214-221.  doi: 10.1016/j.radonc.2017.10.028 PMID:29122359

12.Jasmer B, Muschol-Steinmetz C, Kreis NN, Friemel A, Kielland-Kaisen U, Brüggmann D, Jennewein L, Allert R, Solbach C, Yuan J, Louwen F. Involvment of the oncogene B-cell lymphoma 6 in the fusion and differentiation process of trophoblastic cells of the placenta.  Oncotarget.  2017 Aug 24;8(65):108643-108654.  doi: 10.18632/oncotarget.20586. PMID:29312557

 13.Steinhäuser K, Klöble P, Kreis NN, Ritter A, Friemel A, Roth S, Reichel JM, Michaelis J, Rieger MA, Louwen F, Oswald F, Yuan J.  Deficiency of RITA results in multiple mitotic defects by affectingmicrotubule dynamics.   Oncogene.  2017 Apr;36(15):2146-2159. doi: 10.1038/onc.2016.372. Epub 2016 Oct 10.  PMID 27721410

14.Ritter A, Friemel A, Kreis NN, Louwen F, Yuan J.  Impact of Polo-like kinase 1 inhibitors on human adipose tissue-derived mesenchymal stem cells.  Oncotarget. 2016 Dec;7(51):84271-84285. doi: 10.18632/oncotarget.12482.  PMID: 27713178

15.Kreis NN, Friemel A, Zimmer B, Roth S, Rieger MA, Rolle U, Louwen F, Yuan J.Mitoticp21Cip1/CDKN1A is regulated by cyclin-dependent kinase 1 phosphorylation  Oncotarget. 2016 Aug 2;7(31):50215-50228. doi 10.18632/oncotarget.10330.  PMID: 27384476 

16.Ritter A, Kreis NN, Louwen F, Wordeman L, Yuan J.:Molecular insight into the regulation andfunction of MCAK; Crit Rev Biochem Mol Biol. 2015 Jul-Aug;51(4):228-45.45   doi:  10.1008/10409238.2016.1178705. Epub 2016 May 5. Review. PMID. 27146484

17.Muschol-Steinmetz C, Jasmer B, Kreis NN, Steinhäuser K, Ritter A, Rolle U, Yuan J, Louwen F.: B-cell lymphoma 6 promotes Proliferation and survival of trophoblastic cells. Cell Cycle. 2016 Mar 18;15(6):827-39. doi: 10.1080/15384101.2016.1149273. PMID: 27029530

18.Ritter A, Friemel A, Fornoff F, Adjan M, Solbach C, Yuan J, Louwen F.:Characterization of adipose-derived stem cells from subcutaneous and visceral adipose tissues and thei function in breast cancer cells. Oncotarget. 2015 Oct 27;6(33):344475-93. doi: 10.18632/oncotarget.5922. PMID: 2643968

19.Ritter A, Sanhaji M, Friemel A, Roth S, Rolle U, Louwen F, Yuan J.: Funtional Analysis ofphosphorylation of the mitotic centromere-associated kinesin by Aurora B kinase in human tumor cells.</