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Publikationen

Wichtige Originalpublikationen

2013

Singer OC, Haring HP, Trenkler J, Nolte CH, Bohner G, Neumann-Haefelin T, Hofmann E, Reich A, Wiesmann M, Niederkorn K, Deutschmann H, Bussmeyer M, Mpotsaris A, Stoll A, Bormann A, Petzold GC, Urbach H, Jander S, Turowski B, Weimar C, Schlamann M, Gröschel K, Boor S, Berkefeld J; for the ENDOSTROKE Study  Group. Periprocedural aspects in mechanical recanalization for acute stroke: data from the ENDOSTROKE registry. Neuroradiology. 2013 Jun 28. [Epub ahead of print]

Diener HC, Foerch C, Riess H, Röther J, Schroth G, Weber R. Treatment of acute ischaemic stroke with thrombolysis or thrombectomy in patients receiving anti-thrombotic treatment. Lancet Neurol. 2013 Jul;12(7):677-88.

Luger S, Harter PN, Mittelbronn M, Wagner M, Foerch C. Brain stem infarction associated with familial Mediterranean fever and central nervous system vasculitis. Clin Exp Rheumatol. 2013 May 27.

Mayer CA, Brunkhorst R, Niessner M, Pfeilschifter W, Steinmetz H, Foerch C. Blood levels of glial fibrillary acidic protein (GFAP) in patients with neurological diseases. PLoS One. 2013 Apr 23;8(4):e62101.

De Marchis GM, Katan M, Weck A, Fluri F, Foerch C, Findling O, Schuetz P, Buhl D, El-Koussy M, Gensicke H, Seiler M, Morgenthaler N, Mattle HP, Mueller B, Christ-Crain M, Arnold M. Copeptin adds prognostic information after ischemic stroke: results from the CoRisk study. Neurology. 2013 Apr 2;80(14):1278-86.

Lauer A, Pfeilschifter W, Schaffer CB, Lo EH, Foerch C. Intracerebral haemorrhage associated with antithrombotic treatment: translational insights from experimental studies. Lancet Neurol. 2013 Apr;12(4):394-405.

Foerch C, Rosidi NL, Schlunk F, Lauer A, Cianchetti FA, Mandeville E, Arai K, Yigitkanli K, Fan X, Wang X, van Leyen K, Steinmetz H, Schaffer CB, Lo EH. Intravenous tPA therapy does not worsen acute intracerebral hemorrhage in mice. PLoS One. 2013;8(2):e54203.

Bothe AM, Berkefeld J, Singer OC, Foerch C, Hattingen E. Intracranial Hypotension as an Important Differential Diagnosis of Deep Brain Swelling: A Case Report. Clin Neuroradiol. 2013 Feb 8.

Kashefiolasl S, Foerch C, Pfeilschifter W. Graphite furnace atomic absorption spectrophotometry--a novel method to quantify blood volume in experimental models of intracerebral hemorrhage. J Neurosci Methods. 2013 Feb 15;213(1):147-50

2012

Singer OC, Melber J, Hattingen E, Jurcoane A, Keil F, Neumann-Haefelin T, Klein JC. MR volumetric changes after diagnostic CSF removal in normal pressure hydrocephalus. J Neurol. 2012 Nov;259(11):2440-6.

Foerch C, Lemercier S, Hennerici MG. A beautiful stroke? A side note on the 75th anniversary of the spectacular death of the French organist and composer Louis Vierne (1870-1937). Cerebrovasc Dis. 2012;34(4):322-5.

Den Ruijter HM, Peters SA, Anderson TJ, Britton AR, Dekker JM, Eijkemans MJ, Engström G, Evans GW, de Graaf J, Grobbee DE, Hedblad B, Hofman A, Holewijn S, Ikeda A, Kavousi M, Kitagawa K, Kitamura A, Koffijberg H, Lonn EM, Lorenz MW, Mathiesen EB, Nijpels G, Okazaki S, O'Leary DH, Polak JF, Price JF, Robertson C, Rembold CM, Rosvall M, Rundek T, Salonen JT, Sitzer M, Stehouwer CD, Witteman JC, Moons KG, Bots ML. Common carotid intima-media thickness measurements in cardiovascular risk prediction: a meta-analysis. JAMA. 2012 Aug 22;308(8):796-803.

Bohmann F, Mirceska A, Pfeilschifter J, Lindhoff-Last E, Steinmetz H, Foerch C, Pfeilschifter W. No influence of dabigatran anticoagulation on hemorrhagic transformation in an experimental model of ischemic stroke. PLoS One 2012;7(7):e40804.

Seiler A, Jurcoane A, Magerkurth J, Wagner M, Hattingen E, Deichmann R, Neumann-Haefelin T, Singer OC. T2' imaging within perfusion-restricted tissue in high-grade occlusive carotid disease. Stroke. 2012 Jul;43(7):1831-6.

Lorenz MW, Polak JF, Kavousi M, Mathiesen EB, Völzke H, Tuomainen TP, Sander D, Plichart M, Catapano AL, Robertson CM, Kiechl S, Rundek T, Desvarieux M, Lind L, Schmid C, DasMahapatra P, Gao L, Ziegelbauer K, Bots ML, Thompson SG; PROG-IMT Study Group. Carotid intima-media thickness progression to predict cardiovascular events in the general population (the PROG-IMT collaborative project): a meta-analysis of individual participant data. Lancet. 2012 Jun 2;379(9831):2053-62

Ziegelbauer K, Schaefer C, Steinmetz H, Sitzer M, Lorenz MW. Clinical usefulness of carotid ultrasound to improve stroke risk assessment: ten-year results from the Carotid Atherosclerosis Progression Study (CAPS). Eur J Prev Cardiol. 2012 May 22.

Brunkhorst R, Foerch C. What causes hematoma enlargement in lobar intracerebral hemorrhage?: novel insights from a genetic study. Stroke. 2012 Jun;43(6):1458-9.  

Pfeilschifter W, Bohmann F, Baumgarten P, Mittelbronn M, Pfeilschifter J, Lindhoff-Last E, Steinmetz H, Foerch C. Thrombolysis with recombinant tissue plasminogen activator under dabigatran anticoagulation in experimental stroke. Ann Neurol. 2012 May;71(5):624-33.

Singer OC, Hamann GF, Misselwitz B, Steinmetz H, Foerch C; Arbeitsgruppe Schlaganfall Hessen. Time trends in systemic thrombolysis in a large hospital-based stroke registry. Cerebrovasc Dis. 2012;33(4):316-21.

Foerch C, You Z, Wang H, Lo EH, Whalen MJ. Traumatic brain injury during warfarin anticoagulation: an experimental study in mice. J Neurotrauma. 2012 Apr 10;29(6):1150-5.

Foerch C, Niessner M, Back T, Bauerle M, De Marchis GM, Ferbert A, Grehl H, Hamann GF, Jacobs A, Kastrup A, Klimpe S, Palm F, Thomalla G, Worthmann H, Sitzer M; BE FAST Study Group. Diagnostic accuracy of plasma glial fibrillary acidic protein for differentiating intracerebral hemorrhage and cerebral ischemia in patients with symptoms of acute stroke. Clin Chem. 2012 Jan;58(1):237-45.

Schlunk F, Van Cott EM, Hayakawa K, Pfeilschifter W, Lo EH, Foerch C. Recombinant activated coagulation factor VII and prothrombin complex concentrates are equally effective in reducing hematoma volume in experimental warfarin-associated intracerebral hemorrhage. Stroke. 2012 Jan;43(1):246-9.

2011

Pfeilschifter W, Spitzer D, Pfeilschifter J, Steinmetz H, Foerch C. Warfarin anticoagulation exacerbates the risk of hemorrhagic transformation after rt-PA treatment in experimental stroke: therapeutic potential of PCC. PLoS One. 2011;6(10):e26087.

Becktepe JS, You SJ, Berkefeld J, Neumann-Haefelin T, Singer OC. Clinical outcome after mechanical recanalization as mono- or adjunctive therapy in acute stroke: importance of time to recanalization. Cerebrovasc Dis. 2011;32(3):211-8.

Bevan S, Meidtner K, Lorenz M, Sitzer M, Grant PJ, Markus HS. Adiponectin level as a consequence of genetic variation, but not leptin level or leptin: adiponectin ratio, is a risk factor for carotid intima-media thickness. Stroke. 2011 Jun;42(6):1510-4.

Mayer CA, Pfeilschifter W, Lorenz MW, Nedelmann M, Bechmann I, Steinmetz H, Ziemann U. The perfect crime? CCSVI not leaving a trace in MS. J Neurol Neurosurg Psychiatry. 2011 Apr;82(4):436-40.

Lauer A, Cianchetti FA, Van Cott EM, Schlunk F, Schulz E, Pfeilschifter W, Steinmetz H, Schaffer CB, Lo EH, Foerch C. Anticoagulation with the oral direct thrombin inhibitor dabigatran does not enlarge hematoma volume in experimental intracerebral hemorrhage. Circulation. 2011 Oct 11;124(15):1654-62.

Pfeilschifter W, Czech-Zechmeister B, Sujak M, Mirceska A, Koch A, Rami A, Steinmetz H, Foerch C, Huwiler A, Pfeilschifter J. Activation of sphingosine kinase 2 is an endogenous protective mechanism in cerebral ischemia. Biochem Biophys Res Commun. 2011 Sep 23;413(2):212-7.

Pfeilschifter W, Czech-Zechmeister B, Sujak M, Foerch C, Wichelhaus TA, Pfeilschifter J. Treatment with the immunomodulator FTY720 does not promote spontaneous bacterial infections after experimental stroke in mice. Exp Transl Stroke Med. 2011 Mar 9;3:2.

Lauer A, Schlunk F, Van Cott EM, Steinmetz H, Lo EH, Foerch C. Antiplatelet pretreatment does not increase hematoma volume in experimental intracerebral hemorrhage. J Cereb Blood Flow Metab. 2011 Aug;31(8):1736-42.

Singer OC, Conrad F, Jahnke K, Hattingen E, Auer H, Steinmetz H. Severe meningoencephalomyelitis due to CNS-Toxocarosis. J Neurol. 2011 Apr;258(4):696-8.

Bevan S, Meidtner K, Lorenz M, Sitzer M, Grant PJ, Markus HS. Adiponectin level as a consequence of genetic variation, but not leptin level or leptin: adiponectin ratio, is a risk factor for carotid intima-media thickness. Stroke. 2011 Jun;42(6):1510-4.

Pfeilschifter W, Spitzer D, Czech-Zechmeister B, Steinmetz H, Foerch C. Increased risk of hemorrhagic transformation in ischemic stroke occurring during warfarin anticoagulation: an experimental study in mice. Stroke. 2011 Apr;42(4):1116-21.

2010

Haarmann A, Deiss A, Prochaska J, Foerch C, Weksler B, Romero I, Couraud PO, Stoll G, Rieckmann P, Buttmann M. Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown. PLoS One. 2010 Oct 21;5(10):e13568..

Krakow K, Sitzer M, Rosenow F, Steinmetz H, Foerch C; Arbeitsgruppe Schlaganfall Hessen. Predictors of acute poststroke seizures. Cerebrovasc Dis. 2010;30(6):584-9.

Thompson BB, Béjot Y, Caso V, Castillo J, Christensen H, Flaherty ML, Foerch C, Ghandehari K, Giroud M, Greenberg SM, Hallevi H, Hemphill JC 3rd, Heuschmann P, Juvela S, Kimura K, Myint PK, Nagakane Y, Naritomi H, Passero S, Rodríguez-Yáñez MR, Roquer J, Rosand J, Rost NS, Saloheimo P, Salomaa V, Sivenius J, Sorimachi T, Togha M, Toyoda K, Turaj W, Vemmos KN, Wolfe CD, Woo D, Smith EE Prior antiplatelet therapy and outcome following intracerebral hemorrhage: a systematic review. Neurology. 2010 Oct 12;75(15):1333-42.

van de Loo S, Walter U, Behnke S, Hagenah J, Lorenz M, Sitzer M, Hilker R, Berg D. Reproducibility and diagnostic accuracy of substantia nigra sonography for the diagnosis of Parkinson's disease. J Neurol Neurosurg Psychiatry. 2010 Oct;81(10):1087-92.

Lorenz MW, Schaefer C, Steinmetz H, Sitzer M. Is Carotid Intima Media Thickness Useful for Individual Prediction of Cardiovascular Risk? Ten-year results from the Carotid Atherosclerosis Progression Study (CAPS). Eur Heart J, 2010;31:2041-8.

De Weerd M, Greving JP, Hedblad B, Lorenz MW, Mathiesen EB, O'Leary DH, Rosvall M, Sitzer M, Buskens E, Bots ML. Prevalence of Asymptomatic Carotid Artery Stenosis in the General Population. An Individual Participant Data Meta-Analysis. Stroke. 2010. [Epub ahead of print]

Hattingen E, Jurcoane A, Melber J, Blasel S, Zanella FE, Neumann-Haefelin T, Singer OC. Diffusion tensor imaging in patients with adult chronic idiopathic hydrocephalus. Neurosurgery. 2010;66(5):917-24.

Kurre W, Berkefeld J, Brassel F, Brüning R, Eckert B, Kamek S, Klein GE, Knauth M, Liebig T, Maskova J, Mucha D, Neumann-Haefelin T, Pilgram-Pastor S, Sitzer M, Sonnberger M, Tietke M, Trenkler J, Turowski B; INTRASTENT Study Group. In-hospital complication rates after stent treatment of 388 symptomatic intracranial stenoses: results from the INTRASTENT multicentric registry. Stroke 2010;41:494-8.

Lorenz MW, Bickel H, Bots ML, Breteler MMB, Catapano AL, Desvarieux M, Hedblad B, Iglseder B, Johnsen SH, Juraska M, Kiechl S, Mathiesen EB, Norata GD, Grigore L, Polak J, Poppert H, Rosvall M, Rundek T, Sacco RL, Sander D, Sitzer M, Steinmetz H, Stensland E, Willeit J, Witteman J, Yanez D, Thompson SG. The PROG-IMT Study Group. Individual progression of carotid intima media thickness as a surrogate for vascular risk (PROG-IMT) – rationale and design of a meta-analysis project. Am Heart J, 2010;159:730-736.

2009

Foerch C, Montaner J, Furie KL, Ning MM, Lo EH. Invited Article: Searching for oracles? Blood biomarkers in acute stroke. Neurology. 2009;73(5):393-9.

Pfeilschifter W, Neumann-Haefelin T, Hattingen E, Singer OC. [Cortical venous thrombosis after a diagnostic lumbar puncture]. Nervenarzt. 2009 Oct;80(10):1219-21.

Foerch C, Montaner J, Furie KL, Ning MM, Lo EH. Invited article: searching for oracles? Blood biomarkers in acute stroke. Neurology. 2009 Aug 4;73(5):393-9.

Park KP, Rosell A, Foerch C, Xing C, Kim WJ, Lee S, Opdenakker G, Furie KL, Lo EH. Plasma and brain matrix metalloproteinase-9 after acute focal cerebral ischemia in rats. Stroke. 2009;40(8):2836-42.

Foerch C, Steinmetz H. Left-sided traffic directionality may be the safer "rule of the road" for ageing populations. Med Hypotheses. 2009;73(1):20-3.

Foerch C, Arai K, Van Cott EM, van Leyen K, Lo EH. Rapid reversal of anticoagulation reduces hemorrhage volume in a mouse model of warfarin-associated intracerebral hemorrhage. J Cereb Blood Flow Metab. 2009;29(5):1015-21.

Foerch C, Sitzer M, Steinmetz H, Neumann-Haefelin T; Arbeitsgruppe Schlaganfall Hessen. Future demographic trends decrease the proportion of ischemic stroke patients receiving thrombolytic therapy: a call to set-up therapeutic studies in the very old. Stroke. 2009 May;40(5):1900-2.

Dvorak F, Haberer I, Sitzer M, Foerch C. Characterisation of the diagnostic window of serum glial fibrillary acidic protein for the differentiation of intracerebral haemorrhage and ischaemic stroke. Cerebrovasc Dis. 2009;27(1):37-41.

Singer OC, Neumann-Haefelin T, Hacke W. Multimodale Schlaganfallbildgebung--ein Update. Nervenarzt. 2009;80(2):117-8.

Singer OC, Fiehler J, Berkefeld J, Neumann-Haefelin T. Schlaganfall-MRT zur Abschätzung des Blutungsrisikos bei thrombolytischer Therapie. Nervenarzt. 2009;80(2):130, 132-6.

Debette S, Bevan S, Dartigues JF, Sitzer M, Lorenz M, Ducimetière P, Amouyel P, Markus HS. Fractalkine receptor/ligand genetic variants and carotid intima-media thickness. Stroke 2009;40:2212-4.

Singer OC, Berkefeld J, Lorenz MW, Fiehler J, Albers GW, Lansberg MG, Kastrup A, Rovira A, Liebeskind DS, Gass A, Rosso C, Derex L, Kim JS, Neumann-Haefelin T for the MR Stroke Study Group Investigators. Risk of Symptomatic Intracerebral Haemorrhage in Patients Treated with Intraarterial Thrombolysis. Cerebrovasc Dis. 2009;27:368-74.

Singer OC, Kurre W, Humpich MC, Lorenz MW, Kastrup A, Liebeskind DS, Thomalla G, Fiehler J, Berkefeld J, Neumann-Haefelin T; MR Stroke Study Group Investigators. Risk assessment of symptomatic intracerebral hemorrhage after thrombolysis using DWI-ASPECTS. Stroke 2009;40:2743-8.

Bevan S, Lorenz MW, Sitzer M, Markus HS. Genetic variation in the leukotriene pathway and carotid intima media thickness – a two stage replication study. Stroke 2009;40:696-701.

Lorenz MW, Loesel N, Thoelen N, Gonzalez M, Lienerth C, Dvorak F, Roelz W, Humpich M, Sitzer M. Effects of poor bone window on the assessment of cerebral autoregulation with transcranial Doppler sonography – a source of systematic bias and strategies to avoid it. J Neurol Sci. 2009;283:49-56.

2008

Foerch C, Arai K, Jin G, Park KP, Pallast S, van Leyen K, Lo EH. Experimental model of warfarin-associated intracerebral hemorrhage. Stroke. 2008 Dec;39(12):3397-404.

Rosell A, Foerch C, Murata Y, Lo EH. Mechanisms and markers for hemorrhagic transformation after stroke. Acta Neurochir Suppl. 2008;105:173-8.

Foerch C, Korf HW, Steinmetz H, Sitzer M; Arbeitsgruppe Schlaganfall Hessen. Abrupt shift of the pattern of diurnal variation in stroke onset with daylight saving time transitions. Circulation. 2008 Jul 15;118(3):284-90

Singer OC, Humpich MC, Fiehler J, G.W. Albers, M.G. Lansberg, A. Kastrup, A. Rovira, D.S. Liebeskind, A. Gass, C. Rosso, L. Derex, J.S. Kim, and Neumann-Haefelin T for the MR Stroke Study Group Investigators. Risk of symptomatic intracerebral hemorrhage after thrombolysis assessed by diffusion-weighted imaging. Annals of Neurology 2008 Jan;63(1):52-60.

Kurre W, Berkefeld J, Sitzer M, Neumann-Haefelin T, du Mesnil de Rochemont R. Treatment of symptomatic high-grade intracranial stenoses with the balloon expandable stent. Neuroradiology 2008;50(8):701-8.

Foerch C, Misselwitz B, Sitzer M, Steinmetz H, Neumann-Haefelin T für die Arbeitsgemeinschaft Schlaganfall Hessen. Die Schlaganfallzahlen bis zum Jahr 2050. Deutsches Ärzteblatt, 2008; 105(26): 467-73

Lorenz MW, Stephan C, Harmjanz A, Staszewski S, Buehler A, Bickel M, von Kegler S, Ruhkamp D, Steinmetz H, Sitzer M. Both long-term HIV Infection and Highly Active Antiretroviral Therapy are Independent Risk Factors for Early Carotid Atherosclerosis. Atherosclerosis 2008;196:720-6.

Lorenz MW, Thoelen N, Loesel N, Lienerth C, Gonzalez M, Humpich M, Roelz W, Dvorak F, Sitzer M. Assessment of cerebral autoregulation with transcranial Doppler sonography in poor bone windows using constant infusion of an ultrasound contrast agent. Ultrasound Med Biol. 2008;34:345-53.

Bevan S, Lorenz MW, Sitzer M, Markus HS. Genetic variation in the leukotriene pathway and carotid intima media thickness – a two stage replication study. Stroke, in press.

2007

Foerch C, Wunderlich MT, Dvorak F, Humpich M, Kahles T, Goertler M, Alvarez-Sabín J, Wallesch CW, Molina CA, Steinmetz H, Sitzer M, Montaner J. Elevated serum S100B levels indicate a higher risk of hemorrhagic transformation after thrombolytic therapy in acute stroke. Stroke. 2007 Sep;38(9):2491-5.

Foerch C, Misselwitz B, Humpich M, Steinmetz H, Neumann-Haefelin T, Sitzer M; Arbeitsgruppe Schlaganfall Hessen. Sex disparity in the access of elderly patients to acute stroke care. Stroke. 2007 Jul;38(7):2123-6.

Fiehler J, Albers GW, Boulanger JM, Derex L, Gass A, Hjort N, Kim JS, Liebeskind DS, Neumann-Haefelin T, Pedraza S, Rother J, Rothwell P, Rovira A, Schellinger PD, Trenkler J. Bleeding risk analysis in stroke imaging before thrombolysis (brasil). Pooled analysis of t2-star-weighted magnetic resonance imaging data from 570 patients. Stroke. 2007 Oct;38(10):2738-44.

Schellinger PD, Thomalla G, Fiehler J, Kohrmann M, Molina CA, Neumann-Haefelin T, Ribo M, Singer OC, Zaro-Weber O, Sobesky J. MRI-based and CT-based thrombolytic therapy in acute stroke within and beyond established time windows. An analysis of 1210 patients. Stroke. 2007 Oct;38(10):2640-5.

Kahles T, Luedicke P, Steinmetz H, Neumann-Haefelin T, Busse R, Brandes R. NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke. Stroke. 2007 Nov;38(11):3000-6.

Lorenz MW, Markus HS, Bots ML, Rosvall M, Sitzer M. Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis. Circulation 2007;115:459-67.

Lorenz MW, Karbstein P, Markus HS, Sitzer M. High-sensitivity C-reactive Protein is not associated with carotid intima-media progression: The Carotid Atherosclerosis Progression Study. Stroke 2007;38:1774-9.

Lorenz MW, Graf M, Henke C, Hermans M, Ziemann U, Sitzer M, Foerch C. Anthropometric approximation of body weight in unresponsive stroke patients. JNNP 2007;78:1331-6.

Lorenz MW, Gonzalez M, Lienerth C, Loesel N, Thoelen N, Sitzer M. Influence of temporal insonation window quality on the assessment of cerebral autoregulation with transcranial Doppler sonography. Ultrasound Med Biol 2007;33:1540-5.

Labrum R, Bevan S, Sitzer M, Lorenz M, Markus HS. Toll Receptor Polymorphisms and Carotid Artery Intima-Media Thickness. Stroke 2007;38:1179-84.

Singer OC, Humpich MC, Lanfermann H, Neumann-Haefelin T. Yawning in acute anterior circulation stroke. J Neurol Neurosurg Psychiatry. 2007;78(11):1253-4.

2006

Foerch C, Curdt I, Yan B, Dvorak F, Hermans M, Berkefeld J, Raabe A, Neumann-Haefelin T, Steinmetz H, Sitzer M. Serum glial fibrillary acidic protein as a biomarker for intracerebral haemorrhage in patients with acute stroke. J Neurol Neurosurg Psychiatry. 2006;77:181-184.

Foerch C, Sitzer M, Steinmetz H, Neumann-Haefelin T. Pretreatment with antiplatelet agents is not independently associated with unfavorable outcome in intracerebral hemorrhage. Stroke. 2006 Aug;37(8):2165-7.

Lorenz M, Sterzer P, Sitzer M: Erzielter Blutdruckabfall als Biasfaktor der zerebralen Autoregulationsmessung mit der leg-cuff-Methode. Ultraschall Med 2006; 27: 368-73.

Humpich M, Singer OC, du Mesnil de Rochemont R, Foerch C, Lanfermann H, Neumann-Haefelin T. Effect of early and delayed recanalization on infarct pattern in proximal middle cerebral artery occlusion. Cerebrovasc Dis. 2006;22(1):51-6.

Foerch C, Curdt I, Yan B, Dvorak F, Hermans M, Berkefeld J, Raabe A, Neumann-Haefelin T, Steinmetz H, Sitzer M. Serum glial fibrillary acidic protein as a biomarker for intracerebral haemorrhage in patients with acute stroke. J Neurol Neurosurg Psychiatry. 2006 Feb;77(2):181-4.

Neumann-Haefelin T, Hoelig S, Berkefeld J, Fiehler J, Gass A, Humpich M, Kastrup A, Kucinski T, Lecei O, Liebeskind DS, Rother J, Rosso C, Samson Y, Saver JL, Yan B. Leukoaraiosis is a risk factor for symptomatic intracerebral hemorrhage after thrombolysis for acute stroke. Stroke. 2006;37:2463-2466.

Singer OC, Humpich MC, Laufs H, Lanfermann H, Steinmetz H, Neumann-Haefelin T. Conjugate eye deviation in acute stroke: Incidence, hemispheric asymmetry, and lesion pattern. Stroke. 2006;37:2726-2732.

Lorenz MW, von Kegler S, Steinmetz H, Markus HS, Sitzer M: Carotid intima-media thickening indicates a higher vascular risk across a wide age range: prospective data from the Carotid Atherosclerosis Progression Study (CAPS). Stroke 2006; 37: 87-92.

2005

Foerch C, Singer OC, Neumann-Haefelin T, du Mesnil de Rochemont R, Steinmetz H, Sitzer M. Evaluation of serum s100b as a surrogate marker for long-term outcome and infarct volume in acute middle cerebral artery infarction. Arch Neurol. 2005;62:1130-1134.

Foerch C, Misselwitz B, Sitzer M, Berger K, Steinmetz H, Neumann-Haefelin T. Difference in recognition of right and left hemispheric stroke. Lancet. 2005;366:392-393.

Kahles T, Foerch C, Sitzer M, Schroeter M, Steinmetz H, Rami A, Neumann-Haefelin T. Tissue plasminogen activator mediated blood-brain barrier damage in transient focal cerebral ischemia in rats: relevance of interactions between thrombotic material and thrombolytic agent. Vascul Pharmacol. 2005 Oct;43(4):254-9.

Foerch C, Singer OC, Neumann-Haefelin T, du Mesnil de Rochemont R, Steinmetz H, Sitzer M. Evaluation of serum S100B as a surrogate marker for long-term outcome and infarct volume in acute middle cerebral artery infarction. Arch Neurol. 2005 Jul;62(7):1130-4.

Singer OC, Dvorak F, du Mesnil de Rochemont R, Lanfermann H, Sitzer M, Neumann-Haefelin T. A simple 3-item stroke scale: Comparison with the national institutes of health stroke scale and prediction of middle cerebral artery occlusion. Stroke. 2005;36:773-776

2004

Singer OC, Otto B, Steinmetz H, Ziemann U. Acute neuropathy with multiple conduction blocks after TNFalpha monoclonal antibody therapy. Neurology. 2004 Nov 9;63(9):1754.

Laufs H, Weidauer S, Heller C, Lorenz M, Neumann-Haefelin T. Hemi-spinal cord infarction due to vertebral artery dissection in congenital afibrinogenemia. Neurology 2004;63:1522-3.

Foerch C, Otto B, Singer OC, Neumann-Haefelin T, Yan B, Berkefeld J, Steinmetz H, Sitzer M. Serum s100b predicts a malignant course of infarction in patients with acute middle cerebral artery occlusion. Stroke. 2004;35:2160-2164.

Neumann-Haefelin T, du Mesnil de Rochemont R, Fiebach JB, Gass A, Nolte C, Kucinski T, Rother J, Siebler M, Singer OC, Szabo K, Villringer A, Schellinger PD. Effect of incomplete (spontaneous and postthrombolytic) recanalization after middle cerebral artery occlusion: A magnetic resonance imaging study. Stroke. 2004;35:109-114.

Singer OC, Sitzer M, du Mesnil de Rochemont R, Neumann-Haefelin T. Practical limitations of acute stroke mri due to patient-related problems. Neurology. 2004;62:1848-1849.

Stengel A, Neumann-Haefelin T, Singer OC, Neumann-Haefelin C, Zanella FE, Lanfermann H, Pilatus U. Multiple spin-echo spectroscopic imaging for rapid quantitative assessment of n-acetylaspartate and lactate in acute stroke. Magn Reson Med. 2004;52:228-238.

vor 2004

Lorenz M, Berlit P, Diehl RR: Prädiktoren für die Rückbildung von Gefässprozessen der A. cerebri media. Eine retrospektive Analyse von 90 Patienten. Nervenarzt 2003;74: 343-9.

Singer OC, de Rochemont Rdu M, Foerch C, Stengel A, Lanfermann H, Sitzer M, Neumann-Haefelin T. Relation between relative cerebral blood flow, relative cerebral blood volume, and mean transit time in patients with acute ischemic stroke determined by perfusion-weighted MRI. J Cereb Blood Flow Metab. 2003;23:605-611

Neumann-Haefelin T, Wittsack HJ, Wenserski F, Siebler M, Seitz RJ, Modder U, Freund HJ. Diffusion- and perfusion-weighted MRI. The DWI / PWI mismatch region in acute stroke. Stroke. 1999;30:1591-1597.

Neumann-Haefelin T, Kastrup A, de Crespigny A, Yenari MA, Ringer T, Sun GH, Moseley ME. Serial MRI after transient focal cerebral ischemia in rats: Dynamics of tissue injury, blood-brain barrier damage, and edema formation. Stroke. 2000;31:1965-1972.


Ausgewählte Übersichtsarbeiten:


Neumann-Haefelin T, Moseley ME, Albers GW. New magnetic resonance imaging methods for cerebrovascular disease: emerging clinical applications.
Ann Neurol. 2000;47:559-70.

du Mesnil de Rochemont R, Berkefeld J, Buchkremer M, Arndt H, Neumann-Haefelin T, Singer OC, Steinmetz H, Zanella F, Sitzer M. Langzeitergebnisse nach Behandlung intrakranieller vertebrobasilärer Stenosen mit Stents. Rofo. 2006;178:96-102.

Parmentier-Schwarz M., Berkefeld J, Kurre W, du Mesnil de Rochemont R, Lehr A, Neumann-Haefelin T, Lorenz M, Dietz A, Schmitz-Rixen T, Zanella FE, Steinmetz H, Sitzer M. Endovaskuläre Behandlung extra- und intrakranieller Stenosen hirnversorgender Arterien. Hessisches Ärzteblatt 1/2007.

Neumann-Haefelin T, Steinmetz H. Time is Brain: Is MRI the clock?
Current opinion in Neurology 2007: 20(4): 410-6.

Arbeitsgruppenleiter:

Projektleiter Biomarker und Experimentelle Ischämie
OA PD Dr. Christian Förch
E-Mail: foerch@em.uni-frankfurt.de
Tel.: +49(0)69 6301 6875 o. 6395 (Sekretariat)

Projektleiter Schlaganfallbildgebung
OA PD Dr. Oliver Singer
E-Mail: o.singer@em.uni-frankfurt.de
Tel.: +49(0)69 6301 5942 o. 6395 (Sekretariat)

Projektleiter Epidemiologie, Klinische Studien, Ultraschall
OA PD Dr. Matthias Lorenz
E-Mail: matthias.lorenz@em.uni-frankfurt.de
Tel.: +49(0)69 6301 83059 o. 6395 (Sekretariat)

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